منابع مشابه
Endocrine Therapy for Male Breast Cancer
More than 90% of male breast cancers (MBC) are estrogen receptor positive but unfortunately over 40% are either stage III or stage IV at the time of presentation. This means that for a substantial proportion of patients, endocrine therapy will be used in a palliative role in the management of MBC. Tamoxifen is the main first line agent that is given for both adjuvant treatment and control of ad...
متن کاملEndocrine Therapy for Breast Cancer
In an admirably concise fashion, Dr.Pritchard summarizes the results of trials randomizing tens of thousands of women in order to evaluate various types and uses of endocrine treatment over more than 50 years. I would never have predicted these results when I began my medical career in the early 1970s, or even as late as 1984 when the first overviews of breast cancer therapy were performed by R...
متن کاملEndocrine therapy for breast cancer.
In addition to ovarian ablation by means of surgery or irradiation, a wide variety of endocrine agents are now available for the management of breast cancer, in both the metastatic and adjuvant settings. Currently available endocrine agents include antiestrogens, progestational drugs, and aromatase inhibitors. Randomized trials and meta-analyses have greatly clarified the specific roles of the ...
متن کاملEndocrine Therapy for Breast Cancer
Endocrine therapy is the oldest form of treatment for metastatic breast cancer. The availability of numerous new endocrine agents during the past 10 years has led to significant changes in the use of this form of therapy. This article identifies appropriate candidates for endocrine therapy and describes various treatment options for different subsets of patients with metastatic disease. Overall...
متن کاملAdjuvant endocrine therapy for breast cancer.
Endocrine therapy is a critical part of adjuvant therapy in women with hormone receptor-positive breast cancer, and has been shown to reduce the risk of recurrence and death from breast cancer. For decades, 5 years of tamoxifen has been the standard treatment. For premenopausal women, it remains so, and we await the results of ongoing trials to define the role of ovarian suppression or ablation...
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ژورنال
عنوان ژورنال: Journal of Steroids & Hormonal Science
سال: 2013
ISSN: 2157-7536
DOI: 10.4172/2157-7536.1000112